- Snatcher Project
- Sneaking Suit
- Sniper Wolf
- Sniper rifle
- Snuff
- Sokolov's wife and daughter
- Sokolov Defection
- Sokrovenno
- Solar Bank (MGA card)
- Soldier list
- Soldier quotes in Metal Gear Solid: Peace Walker
- Soldier quotes in Metal Gear Solid V: The Phantom Pain
- Solid Eye
- Solid Eye (hardware)
- Solid Eye (technology)
- Solid Snake
- Solid Snake's Huskies
- Solid Snake's parachuting companions
- Solid Snake (Galuade)
- Solid Snake (Lobito Island)
- Solid Snake (MG) (MGA2 card)
- Solid Snake (MG2) (MGA2 card)
- Solid Snake (MGS1) (MGA2 card)
- Solid Snake (MGS2) (MGA2 card)
- Solid Snake (MGS2) (MGA card)
- Solid Snake (MGS4) (MGA2 card)
- Solid Snake (Operation 747)
- Solid Snake (Super Smash Bros.)
- Solid Snake (disambiguation)
- Solid Sun
- Solidus Snake
- Solidus Snake's exoskeleton
- Solidus Snake (MGA2 card)
- Solis Space & Aeronautics
- Soliton Radar
- Somoza family
- Sonic Eye
- Sons of Big Boss
- Sons of Liberty
- Sons of Liberty (terrorist group)
- Sons of the Patriots
- Sony
- Sophie N'dram
- South
- South America (Guns of the Patriots Incident)
- South American countries
- South American rebel soldiers
- Soviet Union
- Soviet Union government officials
- Soviet bionics engineer
- Soviet company commander (Da Wialo Kallai)
- Soviet engineers
- Soviet lieutenant colonel (Qarya Sakhra Ee)
- Soviet officers
- Soviet patrol base (San Hieronymo Peninsula)
- Soviet scientists
- Soviet soldier (Russian interpreter)
- Soviet soldiers
- Soviet truck driver (Da Wialo Kallai)
- Space Race
- Special Air Service
- Special Camo Soldier
- Special Missions
- Special Movie
- Special forces units
- Specialist Skills in Metal Gear Solid V: The Phantom Pain
- Spetsnaz commander (Da Shago Kallai)
- Spider
- Splint
- Splinter Cell
- Springfield Operator
- Spugmay Keep
- Stalked resistance member
- Starsailor
- Stealth
- Stealth Camouflage
- Stealth Gun
- Stealth aircraft
- Stealth mat
- Stefanie Joosten
- Stephen
- Steve
- Steve Gardner
- Steven (disambiguation)
- Steven Armstrong
- Steven Blum
- Steyr AUG
- Stinger (MGS1) (MGA card)
- Stinger (MGS2) (MGA card)
- Stormbringer
- Strangelove
- Strategist (Operation Snake Eater)
- Stryker
- Stun Grenade (MGA2 card)
- Stun Grenade (MGA card)
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